NASA is possibly the best scientific organization in the United States of America that deals with space exploration. They have educated humanity on the universe and driven technology and ability to their limits and beyond. Here, we will describe 10 of the most large-scale programs of NASA, each of which has left a noteworthy trace in the advancement of space exploration. 

 1. Apollo Program: One of the most famous of all missions, Apollo missions included the legendary Apollo 11 mission in the year 1969, which provided mankind with a life-long vision of the first step of astronauts Neil Armstrong and Buzz Aldrin on the moon. These missions were very successful and significant for the following reasons; Apollo missions paved the way for future manned space missions. 

 2. Voyager Program: The two Voyager spacecraft were sent in 1977; the mission of the twin craft was to study the outer planets. These two probes have served humanity with first detailed pictures of the giant planets, namely Jupiter, Saturn, Uranus, and Neptune and still feeding the Earth with information as they are in the interstellar medium. 

 3. Hubble Space Telescope: Since 1990 and with visibility of 2 meters, the Hubble Space Telescope has revolutionized the field of astronomy. It has photographed distant galaxies, glowing nebulae, and clusters of stars; it has been an important participant in several scientific investigations among which the measurement of the rate at which the universe is expanding. 

 4. International Space Station (ISS): An international project of NASA, Roscosmos, ESA, JAXA, and CSA the ISS is the only habitable artificial satellite in orbit today to have been continuously occupied since November of 2000. It is an experimental facility for probing into scientific problems in a microgravity environment and scientific fields such as biology, physics, etc were promoted. 

 5. Mars Rover Missions: These rovers belonging to NASA have significantly helped in the exploration of Mars such as Spirit, opportunity, curiosity, and perseverance. These rovers have contributed significantly in shedding light on the surface geological processes, Martian climate the existence of water, and the likely existence of life on Mars to support man’s future exploration of space. 

 6. James Webb Space Telescope (JWST): Slated to replace the Hubble Space Telescope, the JWST shall be capable of viewing the universe in infrared which means that astronomers will be able to study the formation of stars and galaxies in more detail. It has the potential to revolutionize the study of astronomy. 

 7. Artemis Program: Artemis, a mission by NASA seeks to have people back on the lunar surface in the next two years and also build sustainable communities. It should be noted that this program is considered a preparation for other missions to Mars and other planets. 

 8. New Horizons Mission: New Horizons was launched in 2006 and in 2015 supplied humanity with the first close-up pictures of Pluto and its moons and a fresh perspective and knowledge about the Kuiper Belt and the frontier of our solar system. 

 9. Cassini-Huygens Mission: Joint with ESA, Cassini Huygens mission sought to study Saturn and its moons from the year 1997 until its end in 2017. The mission offered magnificent pictures and a wealth of data about Saturn’s rings and moons – especially Titan and Enceladus. 

 10. Kepler Mission: Starting in 2009, the Kepler space telescope was specifically created for the detection of exoplanets via observation of stars. The mission has significantly enhanced our understanding of planets beyond our solar system with the detection of thousands of exoplanets and assisting in understanding questions on planetary systems.

These programs are in conformity with the organization’s philosophy of exploring the unexplored and going beyond the frontiers of existing human knowledge. All these missions have brought something new to humanity’s knowledge about the universe, and motivated countless scientists, engineers, and amateurs.