Mosquito bites itch because of the mosquito's saliva.
The saliva contains proteins that prevent your blood from clotting, allowing the mosquito to feed more easily.
It also contains proteins that cause your body to respond negatively.
Your immune system reacts to mosquito saliva by generating histamine, a substance that causes inflammation and itching.
Wash the affected area thoroughly with soap or apply calamine lotion or hydrocortisone cream to relieve irritation and itching.
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